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H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes

In skeletal muscle specifically, MOTS-c has been shown to enhance glucose transporter-4 (GLUT4) translocation to the cell surface, the molecular mechanism by which muscle cells absorb glucose from the bloodstream

150(7):33083317 Manna PR, Soh J-W, Stocco DM (2011) The involvement of specific PKC isoenzymes in phorbol ester-mediated regulation of steroidogenic acute regulatory protein expression and steroid synthesis in mouse Leydig cells

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This was followed by a decline to a median of 530 pmol/L after transitioning to weekly administration at 90 days