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Aggregation happens when peptide molecules stick together, forming larger complexes that may precipitate from solution or lose biological activity

Pre-incubation of cells with BSO, the inhibitor of -glutamylcysteine synthetase, responsible for the first step in intracellular glutathione synthesis did not change the effect of reduced glutathione on cell volume suggesting a mechanism limited to the interaction of extracellular reduced glutathione on cell membrane

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Symptoms include metabolic acidosis, Central Nervous System depression, and respiratory distress

Some offer thorough medical supervision with regular monitoring, while others provide minimal consultation primarily for legal compliance

For more information about how BC Guidelines are developed, refer to the GPAC Handbook available at BCGuidelines.ca: GPAC Handbook