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The following adverse reactions have been reported: dryness and fissuring of paranasal and infraorbital areas, erythema, and stinging

Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons

Some patients need 2 sessions, and somewhat uncommonly, patients have needed 3 sessions to see full clearance of their SKs

Yendamuri S, Vaporciyan AA, Zaidi T, Feng L, Fernandez R, Bekele NB, Hofstetter WL, Jiang F, Mehran RJ, Rice DC, Spitz MR, Swisher SG , Walsh GL, Roth JA, Katz RL

The physiological roles of lysosomes are linked to the control of lysosome position and dynamics via the activity of the kinesin-activating small GTPase ARL8

It could be the pH of the solution you've created being too far from the body's natural pH of around 7.4