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doi: 10.1016/S1350-9462(03)00050-8

Pernicious anemia occurs when the body lacks intrinsic factor, a protein needed to absorb vitamin B12 from food

The nuance goes one step further

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[38] In Hong Kong and India, vitamin B 12 deficiency has been found in roughly 80% of the vegan population

The functional GDH is a hexamer structure composed of two sets of trimers, with each trimer containing ~ 500 amino acids and each monomer possessing a guanosine triphosphate (GTP) binding site and a nicotinamide adenine diphosphate hydride (NADH)/adenosine diphosphate (ADP) binding site, enabling binding of 6 GTP molecules, 6 ADP molecules and 6 NADH molecules with GDH hexamer at its respective allosteric binding sites