Supplements of FOLIC ACID are reported to improve antibody response in animals
doi:10.5606/kbbihtisas.2016.87094
Individuals with B12 deficiencies often experience a reduction in serotonin levels, which decreases mood and energy
It inhibits the growth of bacteria inside the vial after you have punctured the rubber stopper with a needle

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However, several things can inhibit the secretion of intrinsic factors, which in turn decreases the absorption of B12 by around half per dose, regardless of how high the overall dosage level is given