acetyl-l-carnitine tmao effect on heart JCI Trimethylamine N-Oxide and Related Gut

Individual substances cannot fully support this cycle

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Carrard, A

Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)

10.1161/01.ATV.0000189306.99112.4c 238 PaikW

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