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Declaration of competing interest The authors report that there are no competing interests to declare

United States: Not FDA-approved

Cysteine is known to stimulate glutathione synthesis[23], and cysteine availability is often the limiting factor for intracellular glutathione synthesis[24]

Citrate in the TCA cycle can be catalyzed by ATP citrate lyase (ACLY) and released from the mitochondria into the cytoplasm to form cytoplasmic acetyl-CoA, which is the substrate for de novo lipogenesis [67]

Glutathione might be called the antiviralwarrior in the COVID battle, playing a role, one article reported, in antioxidant defense, nutrient metabolism, and regulation of cellular events. Of key importance, its essential to healthy lungs and respiration

The normality of metabolite distributions was assessed using the Shapiro-Wilk test