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(Histamine antagonists are referred to as H2 antagonists because the specific receptor they block is the histamine type 2 receptor.) As histamine is particularly important for the stimulation of acid after meals, H2 antagonists are best taken 30 minutes before meals

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This strong effect often leads to the rapid development of physical and psychological dependence on the drug

"Carrying snacks or a pre-prepared packed lunch when out can help prevent reaching for the biscuit tin or buying cakes with the daily coffee

[1] United States, Department of State, Report upon Weights and Measures, John Quincy Adams, Senate 119 and House 109 of 16th Congress 2nd Session, Boston Public Library (Washington: Printed by Gales & Seaton, 1821), 27, [2] Department of State, Report, 27