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Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)

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Epigenetic modulation of gene expression by dietary isothiocyanates Despite the fact that most work on the cellular effects of ITC relates to their influence on detoxifying enzymes, recent data support the effect of these dietary compounds on the reactivation of epigenetically silenced genes in cancer cells, particularly through the inhibition of HDAC activity ( Reference Dashwood and Ho 52 )

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By identifying specific proteins that are oxidized in response to oxidative stress, researchers can better understand the molecular mechanisms underlying sperm dysfunction and male infertility

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