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Nonuniversality of inflammaging across human populations

Important: This is an educational guide only not medical advice

Luan et al., 2021

Biological activity duration: Despite the short plasma half-life, downstream effects on telomerase expression and pineal regulation persist substantially longer (days to weeks) consistent with Epithalon acting as a signaling molecule triggering longer-lived transcriptional changes rather than direct dose-response activity

Excess inflammatory signaling continues to degrade tissue or disrupt healing

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