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Acetyl-CoA may promote the acetylation of Foxp3 protein by activating lysine acetyltransferases (KATs) and prevent Foxp3 protein ubiquitination degradation, thus helping to maintain the function of Treg cells (161), while NAD+/NADH activates the deacetylase activity of Sirtuin-1 and inhibits Foxp3 protein (162) ( Figure 4B )

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There is a lack of animal experimental research to reveal the molecular and genetic mechanisms of tumorigenesis in IVF-derived offspring

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