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The treatment was 1,000 g of cyanocobalamin (n=54), 1,000 g of cyanocobalamin plus 400 g of folate (n=51), and a placebo (n=57)

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The neurons in the affected network compensate for this weak or absent signals by increasing the number of neuro-transmitter receptors

2015, pp

For people with normal B12 levels, the effect is much less clear, and wed rather tell you that honestly than oversell it