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Indeed, high plasma level of TNF- is associated with a marked increase in CRP and IL-6, suggesting an interrelated stimulation of the entire inflammatory cascade (Xia et al., 2016)

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[DOI] [PubMed] [Google Scholar] 9.Bi Y., Xia H., Li L., Lee R.J., Xie J., Liu Z., Qiu Z., Teng L

Stimuli for this include TNF, DNA damage, and TLR activation, all components of the psoriasis-development pathway, as discussed above