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In a recent statement, they argued that smoking is the single most important entirely preventable cause of ill health, disability and death in the UK, responsible for 80,000 deaths per year

Biomarker studies are helpful, but they have limits: Differences in personal smoking behavior Short study durations Differences between cigarette brands Long-term effects are harder to measure

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While some nicotine e-cigarettes may help some smokers quit, it doesnt look like the devices and e-liquids tested in trials will be a saving grace for most smokers, even when used under clinical supervision